The rally began outside the Federal Building, then moved to a nearby building that houses an Immigration and Customs Enforcement office and court, where a group locked arms Thursday afternoon and blocked elevators.
The group, which included city councilman Larry Gossett, chanted "Obama, you promised; you've got to keep your promise!" They later moved outside and blocked the busy street intersection at Second Avenue and Madison Street.
Supporters carried signs that say "Immigration Reform Now" and "America Show Your Morals."
The rally was organized by the OneAmerica organization. It is calling for pressure on the Obama administration to pass an immigration reform bill this year.